What question did this study set out to answer?

The aim is to investigate the relationship between maternal gestational diabetes mellitus and the risk of atopic dermatitis in children.

April 16, 2026Dermatology and Therapy0 citationsOpen Access

Gestational Diabetes Mellitus Increases the Risk of Atopic Dermatitis in Children: A National Retrospective Study with Analysis by Treatment Modality

SWSarah Weissmann NANir Amitai EHEliya Honig

Key Points

The aim is to investigate the relationship between maternal gestational diabetes mellitus and the risk of atopic dermatitis in children.
Retrospective analysis of national data
Comparison of children with mothers having gestational diabetes versus those without
Assessment of atopic dermatitis incidence in offspring
Increased risk of atopic dermatitis in children born to mothers with gestational diabetes
The association remains significant after accounting for maternal allergic and perinatal factors
Causality cannot be determined due to the study's retrospective nature

Abstract

Maternal GDM is associated with an increased risk of AD in offspring, independent of maternal allergic and perinatal factors, though causality cannot be inferred because of the retrospective study design. These findings may suggest a role of maternal metabolic health in early-life immune and skin barrier development.

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