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January 1, 2026RSC Medicinal Chemistry

Recent Advances in the Development of Acridine-Based Hybrids with Antiproliferative Activity

Mahdi Gallala Najeh Tka Sonia Aroui

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Key Points

The aim is to explore recent developments in acridine-based compounds that can combat cancer cell growth.
Review of recent literature on acridine derivatives
Analysis of their mechanisms of action
Evaluation of antiproliferative effects in cancer models
Acridine-based hybrids demonstrated significant antiproliferative activity
Notable reduction in drug resistance observed
Potential for multi-target therapeutic applications confirmed

Implication

Research reveals acridine-based hybrids show promising antiproliferative activity against cancer, suggesting new treatment options.

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Cite This Study

Gallala et al. (2026) studied this question.

synapsesocial.com/papers/69e07c632f7e8953b7cbdb06 https://doi.org/10.1039/d6md00023a

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