This research aims to explore the role of AKT2 in shaping the tumor immune microenvironment in lung adenocarcinoma.
Analyzed tumor microenvironment characteristics in patients with high AKT2 expression.
Evaluated γδT cells aggregation and Tregs infiltration levels.
High AKT2 expression correlates with reduced γδT cells aggregation.
Significant increase in Tregs infiltration was observed in tumors with high AKT2 expression.
Abstract
Tumor microenvironment in high AKT2 expression patients demonstrated immunosuppressive characteristics such as reduced γδT cells aggregation and increased Tregs infiltration.