Prospective study of reproductive span and menopausal hormone therapy and cognitive decline over 8 years in the Nurses’ Health Study

Key Points

• This research examines the relationship between reproductive span, menopausal hormone therapy use, and cognitive decline.
• Longitudinal analysis of data from the Nurses' Health Study
• Assessment of cognitive function over 8 years
• Comparison of cognitive trajectories based on reproductive span and MHT use
• Longer reproductive span correlated with improved cognitive trajectories
• Menopausal hormone therapy use did not show a protective effect on cognition
• No inversely associated outcome between MHT and cognitive decline observed