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April 16, 2026Organic & Biomolecular Chemistry0 citations

Construction of 2H-1,4-selenazin-3(4H)-one framework via cyclization of pyrazole derivatives bearing chloroacetamide and selenocyanate fragments

TKTatiana A KudryavtsevaEKEkaterina KudryavtsevaBLBoris V. Lichitsky

Key Points

  • The aim is to synthesize a novel class of compounds, specifically substituted 1,7-dihydropyrazolo[4,3-b][1,4]selenazinones.
  • Developed a three-step synthesis method.
  • Started from readily available 5-aminopyrazoles.
  • Utilized cyclization of pyrazole derivatives with chloroacetamide and selenocyanate.
  • Successfully synthesized substituted 1,7-dihydropyrazolo[4,3-b][1,4]selenazin-6(5H)-ones.
  • The method is efficient and can be applied to various pyrazole derivatives.

Abstract

For the first time, we developed an efficient three-step method for the synthesis of substituted 1,7-dihydropyrazolo4,3-b1,4selenazin-6(5H)-ones starting from readily accessible 5-aminopyrazoles. The presented approach is based on preliminary preparation of...

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Cite This Study

Kudryavtseva et al. (2025) studied this question.

synapsesocial.com/papers/69e07d8f2f7e8953b7cbe7ffhttps://doi.org/10.1039/d6ob00263c
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