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Interpretation of TST reactions of <or=18 mm among BCG-vaccinated persons <40 years of age must be done with caution in areas with a low incidence of tuberculosis. In such a population, except for persons who have never been vaccinated, TST reactions of <or=18 mm are more likely to be the result of prior vaccination than infection and should not systematically lead to preventive treatment.
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Tissot et al. (2004) studied this question.
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