Why the study?
Is impaired cerebrovascular reserve capacity associated with recent symptomatic subcortical infarction and multiple silent infarctions in nonstenotic patients with first-ever stroke?
Population
Nonstenotic patients with first-ever stroke who had a recent symptomatic subcortical infarction associated…
Design
Cross-sectional
Authors
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Hypothesis-generating for small vessel vasculopathy in subcortical stroke; does not yet inform clinical decisions in nonstenotic patients.
Is impaired cerebrovascular reserve capacity associated with recent symptomatic subcortical infarction and multiple silent infarctions in nonstenotic patients with first-ever stroke?
Impaired cerebrovascular reserve capacity is strongly associated with subcortical infarctions and multiple silent infarctions, suggesting small vessel vasculopathy and hypoperfusion as pathogenetic mechanisms.
Cupini et al. (2001) studied this question.
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