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January 2, 2023Advanced MaterialsOpen Access

Plant‐Derived Vesicle‐Like Nanoparticles as Promising Biotherapeutic Tools: Present and Future

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Authors

JFJunjie FengHainan UniversityQXQi XiuKey Laboratory of Guangdong ProvinceYHYiyao HuangEast China Jiaotong University

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Implication

Review highlights the therapeutic and drug delivery potential of plant-derived vesicle-like nanoparticles across mammalian disease models, suggesting safe, cost-effective alternatives to synthetic...

Key Points

  • Review the biogenesis, preparation, physicochemical properties, biosafety, and therapeutic applications of plant-derived vesicle-like nanoparticles.
  • Synthesized literature on isolation, characterization, preservation, and biosafety protocols for plant-derived vesicle-like nanoparticles.
  • Evaluated mechanistic evidence concerning interkingdom signaling, molecular cargo delivery, and clinical utility across plant and mammalian disease models.
  • Plant-derived vesicle-like nanoparticles exhibit low immunogenicity, high bio-availability, and the capacity to deliver functional molecular cargo to mammalian cells.
  • Nanoparticles modulate host cell-signaling pathways to regulate disease states, offering potential as standalone therapeutics and engineered drug delivery platforms.
  • Standardization of isolation techniques, purity assays, and preservation methods is required to enable clinical translation.

Cite This Study

Feng et al. (2023) studied this question.

synapsesocial.com/papers/69e1b5823e490517ce86b6fehttps://doi.org/10.1002/adma.202207826
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