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Clinical cases reveal a new technique for shaping advanced platelet-rich fibrin plugs, suggesting improved healing outcomes.
This article presents a novel technique for shaping advanced platelet-rich fibrin (A-PRF) to precisely fill uniform defects while preserving its biological integrity and regenerative capacity, with relevance to Oral & Maxillofacial Surgery. We present two clinical cases illustrating the use of soft tissue punch biopsy tools to accurately shape A-PRF plugs. In each case, appropriately sized punches were used to conform A-PRF to the dimensions of the defect—screw holes following bimaxillary osteotomy, and a sinus tract resulting from post-radiotherapy wound breakdown. The technique enabled precise, easy handling of A-PRF while maintaining its natural structure and biological properties, avoiding the loss of growth factors typically associated with compression. This technique offers a straightforward, predictable method for shaping A-PRF to precisely fit uniform cylindrical defects while preserving the natural fibrin architecture. It has the potential to simplify operative handling and optimise defect adaptation, facilitating optimal healing.
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Shivji et al. (2026) studied this question.
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