What question did this study set out to answer?

The aim is to develop a composite dressing using polycaprolactone, propolis, and silver nanoparticles for improved wound healing.

A Novel Polycaprolactone Composite Nanofiber Dressing Co‐Loaded With Propolis and Silver Nanoparticles for Faster Wound Healing: In Vivo Evidence

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Novel composite dressing enhances wound healing in a rat model, suggesting a multifunctional solution for faster recovery.

The aim is to develop a composite dressing using polycaprolactone, propolis, and silver nanoparticles for improved wound healing.
Fabrication of three types of electrospun nanofiber mats: neat PCL, PCL/PP, and PCL/PP-AgNPs.
In vivo testing in a full-thickness rat wound model over 14 days.
Biochemical analyses of wound microenvironment and organ functions.
The PCL/PP-AgNPs dressing achieved 99.8% wound closure.
Enhanced wound contraction rates and histological improvements observed.
Significant reduction in oxidative stress and pro-inflammatory cytokines.

Ragab et al. (2026) studied this question.

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