Brain magnetic resonance imaging biomarkers for future frailty; sub‐study of FINGER trial

Johanna Pöyhönen; Hanna‐Maria Roitto; Jenni Lehtisalo; E Levälahti; Timo Strandberg; Miia Kivipelto; Riitta Antikainen; Hilkka Soininen; Jaakko Tuomilehto; Tiina Laatikainen; A SOLOMON; Ruth Stephen; Juha Rinne; Eric Westman; Tiia Ngandu

doi:10.1002/alz.71379

April 1, 2026Alzheimer s & DementiaOpen Access

Brain magnetic resonance imaging biomarkers for future frailty; sub‐study of FINGER trial

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Key Points

This research aims to identify brain MRI biomarkers that can predict frailty in older adults.
Analyzed MRI data from participants in the FINGER trial.
Focused on age-related brain changes.
Evaluated the relationship between MRI findings and frailty outcomes.
Identified specific brain biomarkers associated with increased frailty risk.
Suggested that monitoring these biomarkers can aid in future frailty prevention strategies.

Implication

Sub-study reveals biomarkers for frailty in older adults, suggesting insights for prevention strategies.

Abstract

The Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) is registered at ClinicalTrials.gov (no. NCT01041989).

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Cite This Study

Pöyhönen et al. (2026) studied this question.

synapsesocial.com/papers/69e1cf375cdc762e9d85831b https://doi.org/10.1002/alz.71379

View Full Paper

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Brain magnetic resonance imaging biomarkers for future frailty; sub‐study of FINGER trial

Key Points

Implication

Abstract

Discussion

Cite This Study

Brain magnetic resonance imaging biomarkers for future frailty; sub‐study of FINGER trial

Key Points

Implication

Abstract

Discussion

Cite This Study

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