Draft genome sequence of Lentzea sp. H45 from high-altitude Atacama Desert soil

Wei Zhou; Jenileima Kshetrimayum Devi; Nick Allenby

doi:10.1128/mra.01122-25

April 15, 2026Microbiology Resource AnnouncementsOpen Access

Draft genome sequence of Lentzea sp. H45 from high-altitude Atacama Desert soil

View Full Paper

Ask AI

Bookmark

Share

Key Points

This research aims to characterize the genome of Lentzea sp. H45 and its potential for producing bioactive compounds.
Sequencing the draft genome of Lentzea sp. H45
Analyzing genome size and GC content
Identifying biosynthetic gene clusters
The genome size is 8.7 Mbp with 70.9% GC content.
Identified 34 biosynthetic gene clusters.
Contains a putative oligosaccharide cluster linked to lentzeoside biosynthesis.

Implication

Genome sequence reveals anti-HIV-1 integrase compounds in extremotolerant actinobacterium from desert soil, indicating potential therapeutic use.

Abstract

We report the draft genome sequence of Lentzea sp. H45, an extremotolerant actinobacterium from high-altitude Atacama Desert soil, producing anti-HIV-1 integrase lentzeosides. The genome comprises 8.7 Mbp with 70.9% GC content and harbors 34 biosynthetic gene clusters, including a putative oligosaccharide cluster for lentzeoside biosynthesis.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Zhou et al. (2026) studied this question.

synapsesocial.com/papers/69e1cf985cdc762e9d8587cd https://doi.org/10.1128/mra.01122-25

View Full Paper

Ask AI

Bookmark

Share

Draft genome sequence of Lentzea sp. H45 from high-altitude Atacama Desert soil

Key Points

Implication

Abstract

Discussion

Cite This Study

Draft genome sequence of Lentzea sp. H45 from high-altitude Atacama Desert soil

Key Points

Implication

Abstract

Discussion

Cite This Study

Keep reading

Keep reading