Why the study?
Evaluating the extent to which sex and gender differences in Alzheimer's dementia are driven by longevity, survival bias, comorbidities, and other differential risk factors is critical for planning prevention trials.
Design
Review
Authors
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Multiple factors beyond hormones shape sex differences in AD; leaves open whether findings inform sex-specific prevention or care.
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Aggarwal et al. (2023) studied this question.
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