Cumulative Incidence and Risk of Depression After Opioid Use in Head and Neck Cancer Patients

Key Points

• To evaluate the relationship between opioid use and the risk of developing depression in patients after head and neck cancer surgery.
• Examined the impact of long-term opioid therapy (LTOT) on depression risk
• Conducted a retrospective analysis of head and neck cancer patient data
• Assessed cumulative incidence of depression post-surgery
• LTOT is associated with a significantly higher risk of depression after surgery
• Findings indicate that opioid use can complicate mental health outcomes in these patients