Systemic Inflammation and Semen Quality: Associations of Inflammatory Markers With Sperm Parameters Based on the STARR EHR Database

Key Points

• To explore the relationship between systemic inflammation and semen quality using inflammatory markers.
• Analyzed inflammatory indices derived from complete blood count (CBC) data.
• Evaluated associations between inflammatory markers and sperm parameters.
• Focused on testing within 30-90 days of semen analysis.
• NLR, RPR, PLR, and MER were significantly associated with lower semen quality.
• The strongest associations were noted during the 30-90 day testing window.