A Four‐Item Risk Score to Target Acute HIV Infection Testing Among Men Who Have Sex With Men in Indonesia: Development and Validation in the INTERACT Prospective Cohort

L Gilbert; Nurhayati H. Kawi; Hendry Luis; Dwi P. Rahmawati; Erik P. Sihotang; Margareta Oktaviani; Pande Putu Januraga; Suwarti; Evi Sukmaningrum; Evy Yunihastuti; Maartje Dijkstra; Eduard J. Sanders; F. Stephen Wignall; Keerti Gedela; Irwanto; Raph L Hamers; the INTERACT Study Group

doi:10.1002/jia2.70111

April 1, 2026Journal of the International AIDS SocietyOpen Access

A Four‐Item Risk Score to Target Acute HIV Infection Testing Among Men Who Have Sex With Men in Indonesia: Development and Validation in the INTERACT Prospective Cohort

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Key Points

The aim is to develop and validate a four-item risk score to identify acute HIV infection (AHI) in men who have sex with men (MSM) in Indonesia.
Developed a four-item risk score based on easily collected variables.
Validated the score within the INTERACT prospective cohort.
Focused on MSM populations, particularly younger individuals with lower education levels.
Identified specific risk factors associated with acute HIV infection.
Demonstrated that the risk score can effectively target testing efforts in high-yield settings.
Highlighted the vulnerability of younger MSM with lower educational attainment.

Implication

This cohort study develops a risk score to improve acute HIV infection detection among men who have sex with men, highlighting prevention opportunities.

Abstract

This four-item risk score of easily collected variables can facilitate efficient AHI detection in high-yield clinic settings, enhancing opportunities for HIV prevention. In the Indonesian context, younger MSM with lower educational attainment were particularly vulnerable to AHI.

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Cite This Study

Gilbert et al. (2026) studied this question.

synapsesocial.com/papers/69e320af40886becb653fd1a https://doi.org/10.1002/jia2.70111

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A Four‐Item Risk Score to Target Acute HIV Infection Testing Among Men Who Have Sex With Men in Indonesia: Development and Validation in the INTERACT Prospective Cohort

Key Points

Implication

Abstract

Discussion

Cite This Study

A Four‐Item Risk Score to Target Acute HIV Infection Testing Among Men Who Have Sex With Men in Indonesia: Development and Validation in the INTERACT Prospective Cohort

Key Points

Implication

Abstract

Discussion

Cite This Study

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