A microfluidic skin-on-a-chip enabling in situ construction of full-thickness human skin for modeling inflammatory disease

Key Points

• The study aims to create a microfluidic model of full-thickness human skin to better understand inflammatory diseases.
• Developed a microfluidic platform for skin culture.
• Constructed full-thickness human skin using this technology.
• Evaluated responses to inflammatory stimuli.
• The skin-on-a-chip model mimicked natural skin responses.
• Demonstrated potential for drug efficacy assessment.
• Provided insights into inflammatory reactions effectively.