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April 18, 2026BMC Veterinary ResearchOpen Access

The impact of melatonin implants on the fertility of superstimulated donor heifers at subsequent insemination after embryo recovery

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Authors

NDNajmeh DavoodianAKAli KadivarMGMajid Gholami

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Overview

This research evaluates melatonin's effect on fertility in donor heifers after embryo recovery, suggesting potential benefits.

Key Points

  • The aim is to determine if melatonin implants can reduce oxidative stress effects during ovarian superstimulation in donor heifers and enhance fertility outcomes.
  • Twenty-four donor heifers were divided into treatment and control groups.
  • Treatment received melatonin implants while control did not.
  • Blood samples were analyzed for Total Antioxidant Capacity (TAC) and Total Oxidant Status (TOS) to assess oxidative stress index (OSI).
  • Fertility outcomes were measured following artificial insemination (AI) and embryo collection.
  • TAC in the treatment group was significantly higher than in the control group (9.13 vs 6.94 mmol/L, p = 0.00).
  • TOS was significantly lower in the treatment group (7.13 vs 11.78 µmol/L, p = 0.01).
  • OSI was significantly lower in the treatment group (0.79 vs 1.72 AU, p = 0.00).
  • No significant difference in pregnancy rates between the groups (42.85% vs 30% for First AI, p = 0.678).
  • Pregnancy outcomes were not statistically significantly affected by the treatment.

Cite This Study

Davoodian et al. (2026) studied this question.

synapsesocial.com/papers/69e3211640886becb6540455https://doi.org/10.1186/s12917-026-05394-y
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