Cascade synthesis demonstrates efficient production of isoindolone derivatives, indicating a novel chemical approach.
A variety of 2,3-dihydrooxazolo[2,3-a]isoindol-5-one derivatives were synthesized by the DBU-mediated cascade [3+2] annulation reaction of 3-hydroxyisoindolinones with vinylsulfonium salts. A broad range of tricyclic isoindolone products were efficiently prepared in...
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Gou et al. (2026) studied this question.
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