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Randomized controlled trial shows multimodal exercise improves lean mass in individuals with spinal cord injury, suggesting valuable intervention strategies.
A home-based multimodality intervention combining FES-LC, AE, and testosterone was safe and associated with greater improvements in lean mass and hemoglobin. Although between-group differences in aerobic capacity were not statistically significant, greater within-group increases were observed in the multimodality group. These findings may inform future studies of testosterone-augmented exercise interventions for individuals living with SCI.
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Reid et al. (2026) studied this question.
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