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December 1, 1990Proceedings of the National Academy of SciencesOpen Access

Recombinant human DNase I reduces the viscosity of cystic fibrosis sputum.

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Authors

SSSteven ShakAllegheny CollegeDCDaniel J. CaponGalaxy Advanced Engineering (United States)RHRenate HellmissMayo Clinic

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Shak et al. (1990) studied this question.

synapsesocial.com/papers/69e3549bbe8dae5666d37c8bhttps://doi.org/10.1073/pnas.87.23.9188
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Also Consider

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  1. 1Deoxyribonuclease in the Treatment of Purulent Bronchitis1953 · 40 citations
  2. 2Aminoglycoside penetration, inactivation, and efficacy in cystic fibrosis sputum.1985 · 217 citations
  3. 3Physical properties of sputum. VII. Rheologic properties and mucociliary transport.1975 · 65 citations
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  5. 5Dornase Aerosol Effect on Sputum Viscosity in Cases Of Cystic Fibrosis1968 · 72 citations