Immune Response of Neonates Born to Mothers Infected With SARS-CoV-2

Maria Giulia Conti; Sara Terreri; Eva Piano Mortari; Christian Albano; Fabio Natale; Giovanni Boscarino; G Zacco; Patrizia Palomba; Simona Cascioli; Francesco Corrente; Claudia Capponi; Mattia Mirabella; Ane Fernandez Salinas; Alessandra Marciano; Francesca De Luca; Ida Pangallo; Cecilia Quaranta; Claudia Alteri; Cristina Russo; Paola Galoppi; Roberto Brunelli; Carlo Federico Perno; Gianluca Terrin; Rita Carsetti

doi:10.1001/jamanetworkopen.2021.32563

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Abstract

In this cohort study, SARS-CoV-2 spike-specific IgA antibodies were detected in infant saliva, which may partly explain why newborns are resistant to SARS-CoV-2 infection. Mothers infected in the peripartum period appear to not only passively protect the newborn via breastmilk secretory IgA but also actively stimulate and train the neonatal immune system via breastmilk immune complexes.

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Conti et al. (2021) studied this question.

synapsesocial.com/papers/69e354bc47a0b499bcb7377b https://doi.org/10.1001/jamanetworkopen.2021.32563

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Immune Response of Neonates Born to Mothers Infected With SARS-CoV-2

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Immune Response of Neonates Born to Mothers Infected With SARS-CoV-2

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Abstract

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