What question did this study set out to answer?

To explore cardiovascular risk factors in Taiwanese patients with multiple sclerosis and neuromyelitis optica spectrum disorder.

April 19, 2026Journal of the Formosan Medical Association0 citationsOpen Access

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Cardiovascular risk profiles among patients with multiple sclerosis and neuromyelitis optica spectrum disorder in Taiwan

CTChi-Ning TsaiNational Taiwan University YWYi-Chih WangNational Taiwan University Hospital YTYi-Te TsaiNational Taiwan University Hospital

Key Points

To explore cardiovascular risk factors in Taiwanese patients with multiple sclerosis and neuromyelitis optica spectrum disorder.
Analyzed cardiovascular phenotypes in MS and NMOSD patients
Examined prevalence of dyslipidemia and treatment-related risks
Conducted comprehensive risk assessments focusing on metabolic and iatrogenic factors.
MS patients showed a notable 'lipid paradox' indicating low dyslipidemia prevalence but high risk impact
In NMOSD, cardiovascular risks were often linked to medication burden
Specific metabolic assessments were essential for accurate cardiovascular risk evaluation.

Abstract

Taiwanese MS and NMOSD patients exhibit distinct cardiovascular phenotypes. MS is characterized by a "lipid paradox" where dyslipidemia, though less prevalent, serves as a high-potency risk trigger. In NMOSD, cardiovascular risk is treatment-related and masked by high medication burden. Comprehensive risk assessment must prioritize these specific metabolic and iatrogenic factors.

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Cite This Study

Tsai et al. (Wed,) studied this question.

synapsesocial.com/papers/69e470a4010ef96374d8d803 https://doi.org/https://doi.org/10.1016/j.jfma.2026.04.072

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