Why the study?
Managing hypertension in an aging population requires an evidence-based framework tailored to age-related characteristics such as arterial stiffness, salt sensitivity, frailty, orthostatic hypotension, cognitive vulnerability, atrial fibrillation, and multimorbidity.
Population
Older adults with hypertension
Design
Clinical practice guideline using PICO questions, systematic evidence appraisal, and GRADE approach
The 2026 Taiwan Hypertension Society Guidelines for the Management of Hypertension in Older Adults provide an evidence-based framework tailored to the needs of an aging population. Recommendations were developed using PICO-formulated clinical questions, systematic evidence appraisal, and the GRADE approach, integrating evidence from randomized trials, observational studies, and expert consensus. A total of 63 actionable recommendations address diagnostic evaluation, blood pressure measurement and monitoring, lifestyle modification, blood pressure targets, and pharmacological therapy, with input from a multidisciplinary guideline panel and an external interdisciplinary expert committee. The guidelines emphasize age-related characteristics of hypertension, including arterial stiffness, salt sensitivity, frailty, orthostatic hypotension, cognitive vulnerability, atrial fibrillation, and multimorbidity. Standardized blood pressure measurement using validated oscillometric devices and regular out-of-office monitoring are strongly recommended. Blood pressure targets are specified according to age groups and common comorbid conditions. Non-pharmacological interventions, particularly dietary sodium reduction, potassium-enriched salt substitutes, healthy dietary patterns, and physical activity, are encouraged. Pharmacological treatment prioritizes individualized therapy and avoidance of overtreatment, especially in frail older adults. Endorsed by relevant national societies, these guidelines offer a practical approach to improving hypertension management and cardiovascular outcomes in older adults.
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Cheng et al. (2026) studied this question.
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