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April 19, 2026SHILAP Revista de lepidopterologíaOpen Access

An interpretable machine learning model for predicting symptomatic pelvic lymphocele after pelvic lymphadenectomy in cervical cancer

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Authors

YWYiyue WangNTNenghuan TangWZWeimin Zhang

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Overview

Analysis develops a predictive model for symptomatic pelvic lymphocele in cervical cancer, suggesting key risk factors.

Key Points

  • The aim is to create a machine learning model to predict symptomatic pelvic lymphocele after lymphadenectomy in cervical cancer patients.
  • Collected clinical data from 221 cervical cancer patients post-pelvic lymphadenectomy.
  • Conducted univariate analysis to identify risk factors for symptomatic pelvic lymphocele.
  • Developed and validated four predictive models: Logistic Regression, KNN, GBM, and XGBoost.
  • Assessed model performance using AUC, DCA, and Brier Score.
  • Applied SHAP to analyze feature importance.
  • Symptomatic pelvic lymphocele occurred in 19.9% of patients studied.
  • The KNN model showed the best predictive performance (training set AUC = 0.952; test set AUC = 0.832).
  • Diabetes, surgical approach, and preoperative metrics were the most significant predictors identified through SHAP analysis.

Cite This Study

Wang et al. (2026) studied this question.

synapsesocial.com/papers/69e470a4010ef96374d8d818https://doi.org/10.3389/fonc.2026.1754363
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