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The review aims to summarize current and evolving systemic therapies for moderate to severe atopic dermatitis.

Therapeutic Progress in Systemic Treatment of Moderate-to-Severe Atopic Dermatitis

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The review aims to summarize current and evolving systemic therapies for moderate to severe atopic dermatitis.
Reviewed literature from the PubMed database using specific keywords related to atopic dermatitis and therapies.
Compared efficacy and safety profiles of approved agents like biologics and Janus kinase inhibitors.
Summarized key clinical trial data on these therapies.
Recent biologics like dupilumab have significantly improved disease outcomes.
Innovations in treatment have considerably reduced disease burdens.
These therapies represent a paradigm shift in clinical care for atopic dermatitis.

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This review summarizes systemic therapies for moderate to severe atopic dermatitis, highlighting efficacy and safety of new treatments.

Jaskulska et al. (2026) studied this question.

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