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April 19, 2026The Journal of Heart and Lung Transplantation2 citationsOpen Access

Comparison of DCD Heart Transplantation Outcomes in Europe and the US

A comparison of DCD Heart Transplantation in Europe and the United States: A multi-centre, retrospective study

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Authors

JLJohn O. LoucaMÖMarco ÖchsnerASAshish Shah

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Overview

This retrospective study compares DCD heart transplantation outcomes in Europe and the US, highlighting demographic differences and survival rates.

Key Points

  • The central aim is to compare donor and recipient demographics, intraoperative parameters, and outcomes of DCD heart transplantation between Europe and the US.
  • Retrospective observational study across 22 heart transplantation centres in Europe and the US.
  • Included patients undergoing DCD heart transplantation since the initiation of each centre's DCD program until January 1, 2023.
  • Primary outcome measured was 1-year survival; secondary outcomes were major graft dysfunction and cellular rejection incidence.
  • 223 patients from Europe and 281 from the US were included in the analysis.
  • DCD donors in Europe were significantly older than those in the US (37 years vs 28 years; p<0.001).
  • 1-year survival was lower in Europe compared to the US (86.6% vs 91.8%; p=0.043).
  • Survival rates at 1-month and 3-years were comparable between regions.
  • The use of mechanical circulatory-assist post-transplantation was higher in Europe (17.9% vs 11%; p=0.03).

Cite This Study

Louca et al. (2026) studied this question.

synapsesocial.com/papers/69e470a4010ef96374d8d956https://doi.org/10.1016/j.healun.2026.04.007
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Pediatric Heart Transplantation after Declaration of Cardiocirculatory Death2008 · 430 citations
  2. 2Disparities in donor heart acceptance between the USA and Europe: clinical implications2023 · 49 citations
  3. 3Donor age and ischemic time in heart transplantation – implications for organ preservation2024 · 25 citations
  4. 4DCDD heart transplantation with thoraco-abdominal normothermic regional perfusion and static cold storage: The experience in Spain2025 · 25 citations