Extract Langerhans cell histiocytosis (LCH) is a rare neoplastic disease of unknown aetiology driven by various somatic mutations in the mitogen-activated protein kinase (MAPK) pathway 1. LCH is highly heterogeneous and may affect virtually any organ 2. Lung involvement is frequently observed in adult LCH patients, almost exclusively in young smokers of both sexes 3.
Salmona et al. (Thu,) studied this question.