Key result
Single AVP II closure resolves massive mitral PVL and improves HF symptoms in a case report.
Why the study?
Clinical experience with transcatheter paravalvular leak closure remains limited, especially for massive paravalvular leaks managed with a single occluder.
Population
One 69-year-old female with massive mitral paravalvular leak
Comparison
Transcatheter mitral paravalvular leak closure with a single occluder
Design
Case report
Follow-up
Nearly one year
Authors
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May offer option for inoperable massive PVL with HF or hemolysis; extends limited TPVLC experience but remains hypothesis-generating.
Case Report (n=1)
No
This case demonstrates the technical feasibility of using a single oversized occluder for transcatheter closure of a massive, relatively regular-shaped mitral paravalvular leak.
Wang et al. (2026) conducted a case report in Massive mitral paravalvular leak (n=1). Transcatheter mitral paravalvular leak closure with a single Amplatzer Vascular Plug II was evaluated on Resolution of paravalvular leak and clinical improvement. Transcatheter closure of a massive 14x7 mm mitral paravalvular leak using a single 22-16 mm Amplatzer Vascular Plug II occluder successfully resolved regurgitation and improved heart failure symptoms.
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