Case report reveals iron deposition in gastric mucosa in a patient with dyspepsia, suggesting a rare complication of iron therapy.
A BSTRACT Gastric siderosis (GS) is the excess deposition of iron in the gastric mucosa, which is a rare complication of oral and parenteral iron therapy. GS is usually associated with excess iron supplementation; however, therapeutic doses causing GS with mucosal injury is rare. Hence, we present here a case of 69-year-old woman with complaints of dyspepsia and regurgitation in a known case of interstitial lung disease. Gastrointestinal endoscopy revealed blackish pigmentation of the gastric mucosa. On microscopic examination, iron deposition was confirmed by Perl’s stain. Our case showed the overlapping of patterns B and C seen in GS.
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Londhe et al. (2026) studied this question.
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