Systematic review finds that age, obesity, and comorbidities predict biologic response in psoriasis, suggesting targeted treatment approaches.
Older age, higher comorbidity burden, obesity, and special-site involvement are associated with poorer biologic response in psoriasis, whereas family history is associated with better outcomes. These readily available baseline factors facilitate phenotype-based risk stratification and may guide treatment selection in clinical practice.
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Mao et al. (2026) studied this question.
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