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Novel technique demonstrates surfactant-free synthesis of soft nanoparticles, indicating potential for cleaner nanomedicine.
We introduce ICE-grinding, overcoming chemistry constraints and contamination in soft nanoparticle synthesis. Cryogenic vitrification embrittles gels via glassy ice, directing nanoscale fracture while preserving polymer networks for nanomedicine.
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Fu et al. (2026) studied this question.
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