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April 19, 2026BMC Geriatrics0 citationsOpen Access

Association between Mediterranean diet adherence and dyspeptic symptoms in older adults: a cross-sectional study in a geriatric outpatient population

NLNezihe Otay LuleKLKemal Ozan LuleZOZeynel Abidin Ozturk

Key Points

  • This study aims to explore the link between adherence to the Mediterranean diet and the severity of dyspeptic symptoms in older adults.
  • Cross-sectional analysis conducted at a geriatric outpatient clinic.
  • Participants aged ≥ 65 years with chronic dyspeptic complaints were enrolled.
  • Mediterranean diet adherence assessed using the 14-item MEDAS tool.
  • Dyspeptic symptoms evaluated with the SODA scale.
  • Statistical analyses included Pearson correlations and multivariable linear regression.
  • Higher MEDAS scores correlated with lower SODA pain (r = -0.177, p = 0.02).
  • Significant reduction in non-pain symptoms with higher MEDAS scores (r = -0.429, p < 0.001).
  • Greater satisfaction scores associated with higher MEDAS scores (r = 0.431, p < 0.001).
  • Each one-point MEDAS score increase linked to reduced pain (B = -1.50, p = 0.001) and non-pain symptoms (B = -1.66, p < 0.001).
  • Higher satisfaction with gastrointestinal well-being also linked to increased MEDAS scores (B = 0.77, p < 0.001).

Abstract

Dyspeptic symptoms are common in older adults and may impair nutritional status and quality of life. Dietary patterns are increasingly recognized as modifiable determinants of gastrointestinal symptom burden, yet evidence regarding Mediterranean diet adherence and dyspepsia severity in geriatric populations remains limited. We aimed to examine the association between Mediterranean diet adherence and dyspeptic symptom severity—including pain, non-pain symptoms, and symptom-related satisfaction—among adults aged ≥ 65 years presenting with dyspeptic complaints. This cross-sectional study was conducted between January 2023 and December 2024 in a geriatric outpatient clinic at Gaziantep University Training and Research Hospital. Consecutive adults aged ≥ 65 years with dyspeptic symptoms lasting ≥ 4 weeks and adequate cognitive capacity (clinical judgment and/or MMSE ≥ 24) were enrolled. Mediterranean diet adherence was assessed using the 14-item Mediterranean Diet Adherence Screener (MEDAS; score 0–14) and categorized as low (≤ 5), moderate (6–9), or high (≥ 10). Dyspeptic symptoms were evaluated using the interviewer-administered Severity of Dyspepsia Assessment (SODA) scale (pain, non-pain symptoms, satisfaction; 7-day recall). Pearson correlations, one-way ANOVA with appropriate post-hoc tests, and multivariable linear regression analyses were performed; models were adjusted for age, sex, and BMI as clinically relevant covariates. A total of 165 participants were included (70.9% women; mean age 71.47 ± 6.43 years; mean BMI 28.51 ± 4.99 kg/m2). Most exhibited moderate MEDAS adherence (73.9%), while 18.2% had low and 7.9% high adherence. Higher MEDAS scores were associated with lower SODA pain (r = − 0.177, p = 0.02) and non-pain symptom scores (r = − 0.429, p < 0.001), and higher satisfaction scores (indicating better perceived gastrointestinal well-being; r = 0.431, p < 0.001). SODA subscale scores differed significantly across adherence categories (all p < 0.05), whereas BMI did not (p = 0.521). In adjusted regression models, each one-point increase in MEDAS was associated with lower pain (B = − 1.50, p = 0.001), non-pain symptoms (B = − 1.66, p < 0.001), and higher satisfaction (B = 0.77, p < 0.001). Greater Mediterranean diet adherence was independently associated with lower dyspeptic symptom severity and higher symptom-related satisfaction in older adults with dyspepsia. Prospective and interventional studies are warranted to determine whether improving Mediterranean diet adherence can causally reduce dyspeptic symptoms in geriatric care.

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Cite This Study

Lule et al. (2026) studied this question.

synapsesocial.com/papers/69e472fc010ef96374d8ee1bhttps://doi.org/10.1186/s12877-026-07501-y
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