Harnessing Deep Eutectic Solvents and Mesoporous Silica Nanospheres Immobilization for Supercharged Amine Dehydrogenase Catalysis in Continuous Flow

Key Points

• This research aims to improve the efficiency and sustainability of chiral amine synthesis using amine dehydrogenase.
• Utilized deep eutectic solvents for enhanced enzyme activity.
• Immobilized amine dehydrogenase on mesoporous silica nanospheres.
• Conducted continuous flow experiments to assess performance.
• Increased enzyme stability and substrate loading capacity observed.
• Enhanced catalytic efficiency was achieved during continuous flow synthesis.