What question did this study set out to answer?

The aim is to optimize conditions for extracting phenolic compounds from apples using ultrasound-assisted extraction.

April 19, 2026MoleculesOpen Access

Multivariate Optimization of Ultrasound-Assisted Extraction of Phenolic Compounds from Apples

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Optimization study demonstrates enhanced phenolic yield in apples using ultrasound extraction, suggesting effective extraction techniques.

The aim is to optimize conditions for extracting phenolic compounds from apples using ultrasound-assisted extraction.
Utilized response surface methodology to evaluate various extraction parameters.
Assessed factors like extraction temperature, solvent-to-sample ratio, and citric acid concentration.
Validated model predictions experimentally for total phenolic and flavonoid content.
Extraction temperature and solvent-to-sample ratio significantly influenced phenolic recovery.
Optimal conditions for extraction were identified as 55 °C, 10 mL/g SSR, and 0.2% citric acid.
Focused on chlorogenic acid and flavan-3-ols, including catechin and epicatechin, as key compounds.

Melini et al. (2026) studied this question.

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Optimization study demonstrates enhanced phenolic yield in apples using ultrasound extraction, suggesting effective extraction techniques.