Bioinspired antimicrobial peptide hydrogel dressing for the accelerated healing of infected wounds

Kunal Agam Kanaujia; Dilip Kumar Arya; Anit Kumar; Shubham Kanaujiya; Prashant Pandey; Srinivas Ganjipete; Shubhini A. Saraf; Parasuram Pavadai; P.S. Rajinikanth

doi:10.1039/d6tb00151c

January 1, 2026Journal of Materials Chemistry B

Bioinspired antimicrobial peptide hydrogel dressing for the accelerated healing of infected wounds

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Key Points

The aim is to evaluate the effectiveness of a chitosan-based hydrogel dressing for wound healing.
Developed a hydrogel dressing using chitosan enriched with gramicidin and trehalose
Tested the dressing in an infected rat wound model
Assessed antimicrobial activity and wound healing rate
The hydrogel dressing significantly enhanced antimicrobial activity
Accelerated wound healing observed compared to control treatments
Demonstrated synergy between gramicidin and trehalose in promoting healing

Implication

A chitosan-based hydrogel dressing enhances healing in infected wounds, suggesting a new treatment approach.

Abstract

A chitosan (CS)-based hydrogel dressing enriched with gramicidin (GCN) and trehalose (TH) enhances antimicrobial activity and accelerates wound healing in an infected rat wound model.

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Cite This Study

Kanaujia et al. (2026) studied this question.

synapsesocial.com/papers/69e473ff010ef96374d8fcb8 https://doi.org/10.1039/d6tb00151c

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Bioinspired antimicrobial peptide hydrogel dressing for the accelerated healing of infected wounds

Key Points

Implication

Abstract

Discussion

Cite This Study

Bioinspired antimicrobial peptide hydrogel dressing for the accelerated healing of infected wounds

Key Points

Implication

Abstract

Discussion

Cite This Study

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