Finds no significant reduction in mortality with high-flow oxygen in acute hypoxemic respiratory failure, indicating similar outcomes between methods.
Among patients with acute hypoxemic respiratory failure, the use of oxygen delivered through a high-flow nasal cannula did not significantly reduce mortality at day 28. (Funded by the French Ministry of Health and Fisher and Paykel Healthcare; SOHO ClinicalTrials.gov number, NCT04468126.).
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Frat et al. (2026) studied this question.
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