Answers are grounded in this paper and cite their sources.
We have developed and implemented a HWA to aid in the classification of VUSs in genes associated with Lynch syndrome. The work presented here demonstrates that this HWA is able to classify MLH1, MSH2, and MSH6 VUSs as either benign or pathogenic with high accuracy.
No takes yet. Share an insight, caveat, or question.
Morris et al. (2016) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: