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This research aims to analyze the genetic characteristics and circulation patterns of influenza viruses in a local pediatric population.

Molecular epidemiology and genetic characteristics of influenza viruses in a local pediatric population of eastern China, 2024

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This research aims to analyze the genetic characteristics and circulation patterns of influenza viruses in a local pediatric population.
Collected 490 influenza antigen-positive specimens from a pediatric hospital in Qidong, eastern China.
Conducted genome enrichment-based whole-genome sequencing for influenza viruses.
Performed phylogenetic analysis on the sequenced genomes.
Identified A/H1N1 (45.41%), A/H3N2 (18.35%), and B/Victoria (36.24%) co-circulating.
Found two peaks of viral activity in January and December.
Detected specific mutations in hemagglutinin associated with genetic diversity.
Observed 3.65% of A/H1N1 strains carrying the oseltamivir resistance marker NA-H275Y.

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This investigation uncovers genetic features and co-circulation of influenza viruses in children, highlighting regional epidemiology.

Sun et al. (2026) studied this question.

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