Key result
Better patient experience correlates with higher medication adherence in outpatients with depression.
Why the study?
High rates of relapse and disability in depression are largely driven by poor medication adherence, creating a need to evaluate factors like patient experience and psychological contract.
Does patient experience and psychological contract influence medication adherence in outpatients with depression?
Cross-Sectional (n=348)
No
Does patient experience and psychological contract influence medication adherence in outpatients with depression?
Patient experience is positively associated with medication adherence in depression, with psychological contract indirectly affecting adherence by influencing patient experience.
Answers are grounded in this paper and cite their sources.
Improving patient experience may boost antidepressant adherence; hypothesis-generating and should not yet change practice pending RCTs.
Effective antidepressant treatment is one of the most important approaches for alleviating depressive symptoms and reducing the risk of suicide. Nevertheless, the high rates of relapse and disability associated with depression are largely due to patients' poor medication adherence. This study investigated the influence of patient experience and psychological contract on medication adherence of outpatients with depression and sought to identify critical factors that could improve medication adherence and provide effective recommendations for the healthcare system. A cross-sectional survey was conducted in Psychiatric Out-patient department of a tertiary general hospital. A total of 348 participants diagnosed with depression were surveyed by SERVQUAL scale, Psychological Contract Scale and Morisky Scale to assess patient experience, psychological contract and medication adherence, respectively. The mean scores of patient experience, psychological contract, and medication adherence were 7.12 ± 1.25, 3.93 ± 0.36, and 5.32 ± 2.41, respectively. Patient experience and its five dimensions were positively correlated with medication adherence ( P < 0.01). Although the psychological contract was not directly associated with medication adherence, it exerted an indirect effect through its influence on patient experience. Patient experience was positively associated with medication adherence among individuals with depression. Moreover, psychological contract exerted an indirect effect on medication adherence by influencing the quality of the patient experience. These findings highlight the importance of enhancing patient-centered service and fostering trust-based relationships to improve treatment adherence in depressive populations. • Poor medication adherence is a major barrier to effective depression treatment. • Patient experience is positively associated with medication adherence in depression. • Psychological contract indirectly affects adherence by influencing patient experience.
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Wan et al. (2026) conducted a cross-sectional in Depression (n=348). Patient experience and psychological contract was evaluated on Medication adherence (p=< 0.01). Patient experience was positively correlated with medication adherence in outpatients with depression, while psychological contract exerted an indirect effect through patient experience.
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