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Review examines the roles of appetite hormones in obesity, suggesting their impact on energy control.
Obesity is a disease that develops as a result of multifactorial causes such as genetic, environmental, biological, psychosocial, and economic factors, leading to excessive fat accumulation and a body mass index exceeding 30 kg/m 2 . In our bodies, there are appetite-stimulating and suppressing hormones that regulate nutrient intake and control energy metabolism, either directly secreted or via the hypothalamus. This review examines the relationships between obesity and major appetite-suppressing hormones, including the protein-based leptin hormone synthesized from adipose tissue and nesfatin-1, a neurohormone expressed from adipose tissue, pancreas, and brain, as well as ghrelin, a peptide hormone also known as an appetite stimulant.
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Yayla et al. (2024) studied this question.
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