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April 21, 2026Trends in GeneticsOpen Access

Heterogeneity in microbial antibiotic responses: genetic basis and within-host evolution

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Authors

QLQingyun LiuLLLiang-Dong Lyu

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Overview

This review uncovers genetic mechanisms that contribute to antibiotic heterogeneity in bacteria, suggesting implications for treatment strategies.

Key Points

  • The paper aims to explore the complex and varied responses of bacteria to antibiotics, focusing on their genetic underpinnings.
  • Review of existing literature on antibiotic responses in bacteria
  • Discussion of genetic mechanisms affecting antibiotic phenotypes
  • Analysis of within-host evolution and its impact on bacterial behavior
  • Confirmed the existence of varied antibiotic response phenotypes in bacteria
  • Identified genetic mechanisms contributing to this heterogeneity
  • Highlighted the evolutionary implications of these findings for treatment strategies.

Cite This Study

Liu et al. (2026) studied this question.

synapsesocial.com/papers/69e7138bcb99343efc98cf80https://doi.org/10.1016/j.tig.2026.03.008
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