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Clinicians observe genetic factors affecting kidney health in children, suggesting early testing is crucial.
Due to its rarity and phenotype variability, Dent disease is frequently under-recognized by clinicians. As over one-third of patients progress to chronic kidney disease by early adulthood, a high index of clinical suspicion and early genetic testing are essential, alongside rigorous monitoring of kidney function.
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Yang et al. (2026) studied this question.
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