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April 21, 2026CureusOpen Access

Bleeding Frequency and Its Association With Joint Health and Functional Independence in Hemophilia: A Cross-Sectional Study Using the Hemophilia Joint Health Score (HJHS) and Functional Independence Score in Hemophilia (FISH)

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Authors

PMPiyush MalikSASudhir Kumar AtriVCVikas Chaudhary

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Overview

Cross-sectional analysis shows worse joint health and lower independence with higher bleeding frequency in hemophilia, indicating clinical concerns.

Key Points

  • This research aims to evaluate the relationship between bleeding frequency, joint health, and functional independence in individuals with hemophilia.
  • Conducted a cross-sectional study with 100 adults having hemophilia A or B.
  • Assessed joint health using Hemophilia Joint Health Score (HJHS) and functional independence using Functional Independence Score in Hemophilia (FISH).
  • Analyzed bleeding frequency through documented records and its association with joint health and functional outcomes.
  • 90% of participants had hemophilia A, with severe disease in 98%.
  • Mean HJHS score was 15.64, indicating joint damage, and mean FISH score was 29.07, indicating functional independence.
  • Higher bleeding frequency correlated with increased HJHS scores and lower FISH scores, revealing significant associations.

Cite This Study

Malik et al. (2026) studied this question.

synapsesocial.com/papers/69e7138bcb99343efc98d007https://doi.org/10.7759/cureus.107298
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Hemophilias — From Royal Genes to Gene Therapy2001 · 1,101 citations
  2. 2Guidelines for the management of hemophilia2012 · 1,937 citations
  3. 3Hemophilia Joint Health Score, Functional Independence Score in Hemophilia, and Pettersson Score in Pediatric Patients With Severe Hemophilia A2023 · 5 citations
  4. 4Musculoskeletal Complications of Hemophilia2009 · 4 citations
  5. 5Hemophilia joint health score reliability study2006 · 339 citations