Beyond “you are what you eat”: Unlocking gut microbiota‐mediated biotransformation of dietary phytochemicals

April 18, 2026iMetaOmics.Open Access

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Key Points

The research aims to understand how gut microbiota convert dietary phytochemicals into bioactive metabolites, influencing health outcomes.
Comprehensive evaluation of existing biotransformation pathways of phytochemicals.
Integration of multi-omics and bioinformatics to study microbial metabolism.
Identification of specific gut bacteria and enzymes involved in these processes.
Found that gut microbiota significantly affect the efficacy of dietary phytochemicals.
Established distinct metabotypes based on individuals' ability to produce various metabolites.
Proposed a roadmap for developing targeted nutritional interventions leveraging gut metabolites.

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This comprehensive framework explores gut microbiota's role in biotransforming phytochemicals, linking mechanisms to personalized nutrition.

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Yang et al. (2026) studied this question.

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