What question did this study set out to answer?

The review aims to differentiate between low-risk and high-risk cases of uterine leiomyomas to improve patient management.

April 21, 2026Journal of SAFOMSOpen Access

Risk Assessment in Leiomyoma: An Important Tool in Midlife Women

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Review explores risk assessment for leiomyomas in midlife women, highlighting implications for individualized management.

The review aims to differentiate between low-risk and high-risk cases of uterine leiomyomas to improve patient management.
Review of clinical, biochemical, inflammatory, genetic, and metabolomic predictors of fibroid growth.
Evaluation of risk factors for leiomyosarcoma and incorporation of prediction modeling techniques.
Identified age, body mass index, and inflammatory markers as critical predictors of leiomyoma growth.
Highlighted multivariate nomograms as effective tools for identifying at-risk patients.
Summarized risk factors for malignant transformation, enhancing decision-making in clinical practice.

Sarkar et al. (2026) studied this question.

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