Key result
LV replacement fibrosis in mitral valve prolapse is linked to increased cardiovascular events and ventricular arrhythmias.
Why the study?
Is LV replacement myocardial fibrosis detected by cardiac magnetic resonance associated with cardiovascular events and structural alterations in patients with mitral valve prolapse?
Is LV replacement myocardial fibrosis detected by cardiac magnetic resonance associated with cardiovascular events and structural alterations in patients with mitral valve prolapse?
The presence of LV replacement myocardial fibrosis in MVP patients is independently associated with cardiovascular events and arrhythmias, highlighting the value of CMR beyond standard echocardiography.
LV replacement myocardial fibrosis is frequent in patients with MVP; is associated with mitral valve apparatus alteration, more dilated LV, MR grade, and ventricular arrhythmia; and is independently associated with cardiovascular events. These findings suggest an MVP-related myocardial disease. Last, cardiac magnetic resonance provides additional information to echocardiography in MVP.
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Beaufils et al. (2021) studied this question. Left ventricular replacement myocardial fibrosis in mitral valve prolapse is frequent and independently associated with cardiovascular events, ventricular arrhythmia, and LV dilation.
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