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March 12, 2021Circulation155 citations

Replacement Myocardial Fibrosis in Patients With Mitral Valve Prolapse

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ABAnne-Laure Constant Dit BeaufilsOHOlivier HuttinAJAntoine Jobbé‐Duval

Structured PICO

Is LV replacement myocardial fibrosis detected by cardiac magnetic resonance associated with cardiovascular events and structural alterations in patients with mitral valve prolapse?

P
Population
Patients with Mitral Valve Prolapse (MVP)
I
Intervention
Cardiac magnetic resonance (CMR) for the assessment of LV replacement myocardial fibrosis
C
Comparator
Echocardiography
O
Outcome
Cardiovascular eventshard clinical

The presence of LV replacement myocardial fibrosis in MVP patients is independently associated with cardiovascular events and arrhythmias, highlighting the value of CMR beyond standard echocardiography.

Abstract

LV replacement myocardial fibrosis is frequent in patients with MVP; is associated with mitral valve apparatus alteration, more dilated LV, MR grade, and ventricular arrhythmia; and is independently associated with cardiovascular events. These findings suggest an MVP-related myocardial disease. Last, cardiac magnetic resonance provides additional information to echocardiography in MVP.

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Cite This Study

Beaufils et al. (2021) studied this question.

synapsesocial.com/papers/69e77b2796fd5f1a11e40b4dhttps://doi.org/10.1161/circulationaha.120.050214
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