This first comprehensive gene expression study of ASPS identifies potential targets for understanding its pathogenesis and developing treatments.
Hypothesis-generating targets in ASPS models; leaves open human validation before therapeutic pursuit.
Results from this first comprehensive study of ASPS gene expression identifies several targets involved in angiogenesis, metastasis and myogenic differentiation. These efforts represent the first step towards defining the cellular origin, pathogenesis and effective treatment strategies for this atypical malignancy.
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Stockwin et al. (2009) studied this question.
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