Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
April 22, 2026Progress in Neuro-Psychopharmacology and Biological PsychiatryOpen Access

MicroRNAs as potential biomarkers in schizophrenia: Current methodological limitations and challenges

View Full Paper
Ask AI
Bookmark
Share

Authors

MHMar HernaezEPEduard ParelladaMBMercè Brunet

Discussion

Loading...

Member takes

Overview

This review evaluates microRNAs as biomarkers and current challenges in schizophrenia diagnosis and treatment monitoring.

Key Points

  • The aim is to assess the potential of microRNAs as biomarkers for schizophrenia and identify methodological limitations.
  • Review of literature on microRNA roles in schizophrenia
  • Analysis of detection techniques like PCR and next-generation sequencing
  • Evaluation of microRNAs linked to schizophrenia and their regulatory pathways
  • MicroRNAs are consistently dysregulated in individuals with schizophrenia
  • No robust biomarker panel has been established despite reported associations
  • Current detection methods face inconsistencies and methodological gaps

Cite This Study

Hernaez et al. (2026) studied this question.

synapsesocial.com/papers/69e864866e0dea528dde95ffhttps://doi.org/10.1016/j.pnpbp.2026.111709
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1MicroRNAs as biomarkers and molecular mediators of cognitive dysfunction in schizophrenia2025
  2. 2MicroRNAs as Potential Biomarkers of Mental Disorders: Diagnostic and Prognostic Implications2024
  3. 3The Role of MicroRNAs as Biomarkers in Neuropsychiatric Disorders.2026
  4. 4Downregulation of miR-29a as a possible diagnostic biomarker for schizophrenia2024 · 4 citations
  5. 5Misdiagnoses of psychiatric disorders and the utility of diagnostic microRNA biomarkers2024 · 5 citations