Findings reveal glymphatic dysfunction affects brain health in individuals with spinocerebellar ataxia type 3, suggesting potential pathways for intervention.
Our findings demonstrate that glymphatic function is impaired, particularly in the presymptomatic stage of SCA3, and this impairment is associated with disability, neurodegeneration, and demyelination. Therefore, glymphatic dysfunction may contribute to the pathogenesis of SCA3.
No takes yet. Share an insight, caveat, or question.
J et al. (2026) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: